Many common herbal supplements interact with common heart medicines. This is not a complete list of possible side effects. Try our Symptom Checker Got any other symptoms? Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. AHFS Patient Medication Information. If it is within 2 hours of the next dose, skip the missed dose. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. Isosorbide tablets are also used with other medications to treat heart failure. Call your doctor if you have any unusual problems while you are taking this medication. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. http://www.upandaway.org. If you have any problems with the way your liver works, or any problems with the way your kidneys work. I took this for 4 days, and my headaches were unbearable. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. US residents can call their local poison control center at 1-800-222-1222. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 8.0 out of 10 from a total of Drug interactions may change how your medications work or increase your risk for serious side effects. Nitrates in the management of acute coronary syndrome. You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. Accessed Sept. 7, 2022. Isosorbide mononitrate helps to prevent angina chest pain from developing. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Isosorbide controls chest pain but does not cure coronary artery disease. Take care, thanks. . it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . This medication belongs to a class of drugs known as nitrates. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. You can start a phase IV clinical trial to monitor Isosorbide mononitrate safety and effectiveness. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). May also be prescribed off label for Esophageal Spasm. eCollection 2021. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. 2017; doi:10.1016/j.jacc.2016.11.078. It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction. Please upgrade your browser or download modern browsers from here! Please note that only the generic name of each medication is listed below. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Cleophas TJ, Niemeyer MG, van Der Wall EE. If you miss a dose, take it as soon as you remember. 19 are major, 174 are moderate, and 2 are minor. All rights reserved. Longer-acting tablets and capsules are taken once daily in the morning. Murray MT. tell your doctor if you may be dehydrated, if you have recently had a heart attack, or if you have or have ever had heart failure, low blood pressure, or hypertrophic cardiomyopathy (thickening of the heart muscles). Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. Garlic. Then, there was a two-week placebo washout, after which the alternative treatment was given. Copyright 2023 IBM Watson Health. The effects of this exposure on a nursing infant are unknown. Click here for an email preview. Herbal supplements can strongly affect the body. If you have an eye condition called glaucoma. May also be prescribed off label for Esophageal Spasm. information and will only use or disclose that information as set forth in our notice of Coenzyme Q-10 Natural Medicines. It is important that you follow the instructions your doctor gives to you about when to take your doses. Isosorbide dinitrate dose 30-120 mg daily in divided doses. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. Isosorbide mononitrate systemic 60 mg (A ID). Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). It is important to take the drug at the same times each day. Store in a cool, dry place, away from direct heat and light. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". Mayo Clinic. This makes it easier for your heart to pump, relieving heart-related chest pain. Keep this medication in the container it came in, tightly closed, and out of reach of children. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). This medicine is available only with your doctor's prescription. Accessed Sept. 7, 2022. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. Take this medication by mouth as directed by your doctor, usually twice a day. The most common side-effect is headache. This should pass after a few days. This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. All rights reserved. In case of overdose, call the poison control helpline at 1-800-222-1222. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. This is called a medicine interaction. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). Data were assessed for carryover and time effects. Higher dosages are associated with stomach irritation and Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. The herb licorice may lower warfarin levels and can add to digoxin's effects. Drug information provided by: IBM Micromedex. These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). You will find a full list in the manufacturer's information leaflet supplied with your medicine. 2023 Lybrate, Inc. All rights reserved. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. What are the interactions of Isosorbide Mononitrate ? The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Your dose may need to be gradually decreased. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Natural Medicines. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). Generic alternatives may be available. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Accessed Sept. 7, 2022. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). Take them to your local pharmacy which will dispose of them for you. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. https://naturalmedicines.therapeuticresearch.com. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. information submitted for this request. Sept. 26, 2022. Who should not take Isosorbide Mononitrate? The most common side-effect is headache. other information we have about you. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). Isosorbide mononitrate: isosorbide mononitrate. All rights reserved. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Before For details see our conditions. information highlighted below and resubmit the form. My EKG showed Assess your symptoms online with our free symptom checker. It will not treat an angina attack that has already begun. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). This does not necessarily mean no interactions exist. The tablet usually is taken two or three times daily. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. If you are a Mayo Clinic patient, this could The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. This should pass after a few days. Other medications may be prescribed by your doctor for these conditions. Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. Herbal medications in cardiovascular medicine. Highly clinically significant. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Yet many herbal supplements may interact with heart disease medicines. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . Patient is a UK registered trade mark. Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Your doctor may tell you to take a pain reliever to treat your headaches. No you may not. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). In: Current Medical Diagnosis & Treatment 2022. Browse Drugs and Medicines. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Does Viagra add to the risks of melanoma? If this worries you, talk to your doctor or pharmacist about other options. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. Never take more than the prescribed dose. All Rights Reserved. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. https://www.uptodate.com/contents/search. Unless your doctor tells you otherwise, continue your normal diet. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not start, stop, or change the dosage of any medicines without your doctor's approval. This is called a medicine interaction. https://naturalmedicines.therapeuticresearch.com. It is best not to drink alcohol while you are on isosorbide mononitrate. Some of these medicine interactions can be risky. Diabetes treatment: Can cinnamon lower blood sugar? 72% of reviewers reported a positive effect, while 12% reported a negative effect. If you forget to take a dose, take it as soon as you remember. Take isosorbide exactly as directed. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. View interaction reports for isosorbide mononitrate and the medicines listed below. Overview of herbal medicines and dietary supplements. Talk to your doctor about the possible risks of using this medication for your condition. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Headache is often a sign that this medication is working. Patient does not provide medical advice, diagnosis or treatment. St. John's wort. Do not keep out-of-date or unwanted medicines. Natural Medicines. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . If we combine this information with your protected Do not let anyone else take your medication. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. May also be prescribed off label for Esophageal Spasm. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. This site complies with the HONcode standard for trustworthy health information: verify here. You may report side effects to the FDA at 1-800-FDA-1088. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. This information is aggregated and used to produce personalized reports that patients can reference. However, you should not flush this medication down the toilet. If you notice other effects not listed above, contact your doctor or pharmacist. 2010; doi:10.1016/j.jacc.2009.07.074. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Portions of this document last updated: Feb. 01, 2023. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. This site complies with the HONcode standard for trustworthy health information: verify here.
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