five basic components of the pupillary light reflex pathway

From the pretectal nucleus, axons connect to neurons in the Edinger-Westphal nucleus, whose axons run along both the left and right oculomotor nerves. This cookie is set by GDPR Cookie Consent plugin. Figure 7.5 a picture of the sun), elicits a stronger pupillary constriction than an image that is perceived as less bright (e.g. Physical examination determines that touch, vibration, position and pain sensations are normal over the entire the body and over the lower left and right side of his face. In human nervous system: Reflex actions. We also get your email address to automatically create an account for you in our website. Palpebral oculogyric reflex (Bells reflex). photoreceptors(receptor):optic nerve(sensory neuron):mid Once your account is created, you'll be logged-in to this account. The foliage, stem and sepals are covered with thousands of fine hairs that protect the bud and plant . The ciliary muscles are innervated by the postganglionic parasympathetic axons (short ciliary nerve fibers) of the ciliary ganglion. {\displaystyle D} Parasympathetic Innervation of the Eye. Based on the above reasoning, the lesion must involve segment 1. The consensual response is the change in pupil size in the eye opposite to the eye to which the light is directed (e.g., if the light is shone in the right eye, the left pupil also constricts consensually). Pupillary Light Reflex Pathway - Video Lecture - MADE EASY - DailyMedEd.com equalize pressure between the environment and the middle ear, A&P I Chapters 14 and 15 Lab - Autonomic Nerv, Myer's AP Psychology: Unit 5 Review (TO COMBI. Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. The accommodation (near point) response is consensual (i.e., it involves the actions of the muscles of both eyes). Pupillary Light Reflex Article - StatPearls Francis, IC, Loughhead, JA. Thus, the Pupillary Light Reflex Pathwayregulates the intensity of light entering the eye by constricting or dilating the pupils. CONTINUE SCROLLING OR CLICK HERE. Examples of segment 1 pathologies include left optic neuritis (inflammation or infection of the left optic nerve), detachment of left retina, and an isolated small stroke involving only the left pretectal nucleus. 447). Section of the facial nerve on one side will result in paralysis of the muscles of facial expression on the ipsilesional side of the face. are respectively the current and previous simulation times (times since the simulation started) measured in milliseconds, https://www.aao.org/bcscsnippetdetail.aspx?id=767021d9-21a5-4b76-af43-49468a5bbd0c, https://www.aao.org/bcscsnippetdetail.aspx?id=3d31809c-9673-453c-a6c7-018c4540e6f9, https://eyewiki.org/w/index.php?title=Reflexes_and_the_Eye&oldid=83681. Abnormal pupillary light reflex can be found in optic nerve injury, oculomotor nerve damage, brain stem lesions, such as tumors, and medications like barbiturates. Observe the reaction to a wisp of cotton touching the patient's left and right cornea. {\displaystyle T_{c}} The iris dilator is controlled by the sympathetic nervous system. Symptoms. We use our eyes to monitor our external environment and depend on our ocular motor systems to protect and guide our eyes. In a normal response of the pupillary light reflex, shining a light into the eye causes constriction of its pupil. Argyll Robertson pupil is found in late-stage syphilis, a disease caused by the spirochete Treponema pallidum. An excellent way to test your knowledge of the material presented thus far is by examining the effects of damage to structures within the ocular motor pathways. What are the five methods of dispute resolution? The receptor potential is generated at the _______. A combined lesion in segments 3 and 5 as cause of defect is very unlikely. document.getElementById("ak_js_1").setAttribute("value",(new Date()).getTime()); document.getElementById("ak_js_2").setAttribute("value",(new Date()).getTime()); All theinformation on this website is intended for educational purposes only, and should not be interpreted as medical advice. Repeat this procedure on the opposite eye. This area was spared by syphilis. d The pupillary light reflex pathway. It usually follows a Bells palsy or traumatic facial paralysis, and occurs due to misdirection of regenerating gustatory fibers from either the facial or glossopharyngeal nerves that are responsible for taste. The left direct reflex is lost. An abnormal plantar reflex in an adult produces Babinski's sign, which indicates ________. The medial rectus is innervated by motor neurons in the oculomotor nucleus and nerve. Observation: You observe that the patient's pupils, Side & Level of damage: As the pupillary light response deficit involves. Ophthalmologic considerations: Abnormalities in this pathway may cause hypolacrimation, hyperlacrimation, or inappropriate lacrimation[4]. The iris sphincter is innervated by the postganglionic parasympathetic axons (short ciliary nerve fibers) of the ciliary ganglion (Figure 7.3). The visual pathway and pupillary light reflex pathway are complex coordinated systems in which multiple components participate with precision. Pupil: Physiology and Abnormalities | Concise Medical Knowledge - Lecturio He has normal ocular mobility and his eyelids can be elevated and depressed at will. It is hypothesized that it is due to oculomotor disinhibition. It consists of a pupillary accommodation reflex, lens accommodation reflex, and convergence reflex. Is there a database for insurance claims? Side & Level of damage: As the ocular loss involves. It will also paralyze the medial, superior & inferior rectus muscles and the inferior oblique, which will allow the lateral rectus to deviate the eye laterally and the superior oblique to depress the eye. This helps to protect the photoreceptors in the retina from damage as a result of bright light. What is the major purpose for vitreous humor? Pupillary reflex is synonymous with pupillary response, which may be pupillary constriction or dilation. Module 19: The Reflex Arc Flashcards | Quizlet A patient is capable of pupillary constriction during accommodation but not in response to a light directed to either eye. Papillary muscle definition, one of the small bundles of muscles attached to the ventricle walls and to the chordae tendineae that tighten these tendons during ventricular contraction. The functions of the pupillary responses include ________. The response is consensual (i.e., bilateral) - involving automatic eyelid closure at both eyes. A single lesion anywhere along segment 1, the left afferent limb, which includes the left retina, left optic nerve, and left pretectal nucleus, can produce the light reflex abnormalities observed. Afferent signals from the left eye cannot pass through the transected left optic nerve to reach the intact efferent limb on the left. View chapter Purchase book Pupil P.D.R. For example, if a bright stimulus is presented to one eye, and a dark stimulus to the other eye, perception alternates between the two eyes (i.e., binocular rivalry): Sometimes the dark stimulus is perceived, sometimes the bright stimulus, but never both at the same time. The receptor is the site of stimulus action. Abducens nucleus is incorrect as it is not involved in pupillary responses. PUPILLARY REFLEXES:- There are all total three pupillary reflexes - Light reflex, Near reflex and Psychosensory reflex. I love to write and share science related Stuff Here on my Website. 1999;90(4):644-646. , which can be described as The visual system provides afferent input to ocular motor circuits that use visual stimuli to initiate and guide the motor responses. Lesions may affect the nervus intermedius, greater superficial petrosal nerve, sphenopalatine ganglion, or zygomaticotemporal nerve. The accommodation response of the lens: comparing the lens shape during near vision (contraction of the ciliary muscle during accommodation) with lens shape during distance vision (relaxation of the ciliary muscle). If his acceleration is the same size at two points, display that fact in your ranking. Figure 7.7 It does not store any personal data. Ophthalmologic considerations: An abnormal VOR will involve catch-up saccades while the patient rotates his or her head, and it can indicate bilateral, complete, or severe (>90%) loss of vestibular function[9]. The motor losses may be severe (i.e., a lower motor neuron loss that produces total paralysis) if the cranial nerve contains all of the motor axons controlling the muscles of the normally innervated area. Sensory transduction is defined as _______. You also have the option to opt-out of these cookies. Sensory neuron #2. In contrast, voluntary eye movements (i.e., visual tracking of a moving object) involve multiple areas of the cerebral cortex as well as basal ganglion, brain stem and cerebellar structures. Dragoi, Valentin. Pupillary escape is an abnormal pupillary response to a bright light, in which the pupil initially constricts to light and then slowly redilates to its original size[4]. What is the role of the pharyngotympanic tube? Recall that the optic tract carries visual information from both eyes and the pretectal area projects bilaterally to both Edinger-Westphal nuclei: Consequently, the normal pupillary response to light is consensual. {\displaystyle \Phi =IA} has not lost cutaneous sensation in the upper left face area, does not blink when his left cornea is touched, both reflex and voluntary motor functions, a branch of the nerve innervating the upper face, a lower motor neuron paralysis of the left orbicularis oculi, motor innervation on the left side (i.e., the symptoms are ipsilesional), responds with direct and consensual eye blink when his right cornea is touched, has lost cutaneous sensation in the upper left face area, a loss of the afferent limb of the eye blink response, the innervation of the left side (i.e., the symptoms are ipsilesional), a left pupil that does not react to light directly or consensually, a right pupil that reacts to light directly and consensually, not sensory (the right pupil reacts to light directed at the left eye), the pupillary light reflex pathway (Figure 7.11), does not involve eyelid or ocular motility, is limited to pupil constriction in the left eye, involves the motor innervation of the left iris sphincter, involves structures peripheral to the oculomotor nucleus (i.e., eye movement unaffected), involves the ciliary ganglion or the short ciliary nerve, is on the left side (i.e., the symptoms are ipsilesional), has not lost cutaneous sensation in the face area, cannot adduct his left eye (i.e., move it toward the nose), has a left dilated pupil that is non reactive to light in either eye, the pupillary/oculomotor pathway (Figure 7.11), is a lower motor neuron paralysis of the superior levator palpebrae, is a lower motor neuron paralysis of the medial, superior & inferior rectus muscles and inferior oblique muscles of the eye, is an autonomic disorder involving the axons of the Edinger-Westphal nucleus, respond when light is directed into either eye, has weaker direct and consensual responses to light directed in the left eye, the pupillary light reflex pathway (Figure 7.11), is in the afferent limb of the pupillary light response, produced a left pupillary afferent defect, do not respond when light is directed into the either of his eyes, motor (the pupillary light responses in both eyes are absent), higher-order motor (because he has a normal pupillary accommodation response), accommodation pathway have not been damaged (Figure 7.14), pupillary light reflex pathway have been damaged (Figure 7.11), does not involve the pupil accommodation response, involves only the pupillary light reflex response. Receptor, sensory neuron, integration center, motor neuron and effector. Sharma D, Sharma N, Kumar Mishra A, Sharma P, Sharma N, Sharma P. POSTOPERATIVE NAUSEA AND VOMITING: A REVIEW. where Read More. {\displaystyle \tau } The left consensual reflex is lost. Get plagiarism-free solution within 48 hours, Submit your documents and get free Plagiarism report, Your solution is just a click away! The lines beginning with a dot indicate axons originating in the structure containing the dot. Ophthalmologic considerations: This reflex is sometimes observed during strabismus surgery[20]. However, he reports that pinpricks to rest of his face are painful. In this video, Dr Matt explains the physiology and some clinical implications of the pupil light reflex and the accommodation reflex Convergence in accommodation: When shifting one's view from a distant object to a nearby object, the eyes converge (are directed nasally) to keep the object's image focused on the foveae of the two eyes. Inappropriate lacrimation can occur with the gustolacrimal reflex, described below. Observe the reaction of the patient's pupils to light directed in the left or right eye. The pupillary light reflex (PLR) or photopupillary reflex is a reflex that controls the diameter of the pupil, in response to the intensity (luminance) of light that falls on the retinal ganglion cells of the retina in the back of the eye, thereby assisting in adaptation of vision to various levels of lightness/darkness. Tactile stimulation of the cornea results in an irritating sensation that normally evokes eyelid closure (an eye blink). Ophthalmologic considerations: Testing of the pupillary light reflex is useful to identify a relative afferent pupillary defect (RAPD) due to asymmetric afferent output from a lesion anywhere along the afferent pupillary pathway as described above[1]. myasthenia gravis, botulism toxin, tetanus), focal or generalized neurologic disease (e.g. Vestibular reflexes and The crossed extensor reflex is an example of a(n) ________. [2] Whereas, the pupil is the passive opening formed by the active iris. That is, a light directed in one eye results in constriction of the pupils of both eyes. The pupillary light reflex allows the eye to adjust the amount of light that reaches the retina. The accommodation response involves three actions: Pupil accommodation: The action of the iris sphincter was covered in the section on the pupillary light reflex. What is the major role of the basilar membrane? Segments 7 and 8 each contains parasympathetic fibers that courses from the Edinger-Westphal nucleus, through the ciliary ganglion, along the oculomotor nerve (cranial nerve #3), to the ciliary sphincter, the muscular structure within the iris. Papillary muscle Definition & Meaning | Dictionary.com Multiple sclerosis, which often affects multiple neurologic sites simultaneously, could potentially cause this combination lesion. The nurse is assessing a patients eyes for the accommodation response and would expect to see which normal finding? Contents 1997-Present - McGovern Medical School at UTHealth The patient complains of reduced vision in the left eye. Autonomic reflexes: activate cardiac muscles, activate smooth muscles, activate glands. The ipsilateral efferent limb transmits nerve signals for direct light reflex of the ipsilateral pupil. 2. The efferent (motor) pupillary pathway has both parasympathetic and sympathetic nervous system actions. Which of the following components is the integration center of the patellar reflex arc? Segments 3, 4, 5, and 6 are all located within a compact region within the midbrain. Light is the stimulus; impulses reach the brain via the optic nerve; and the response is conveyed to the pupillary musculature by autonomic nerves that supply the eye. The cookies is used to store the user consent for the cookies in the category "Necessary". Neuro-ophthalmology Illustrated Chapter 12 - The Pupil 2 7.2 Ocular Reflex Responses Reflexes are involuntary responses, usually asso- ciated with protective or regulatory functions in the organism in which they occur. Which of the following will cause the reaction time of a reflex to increase? The reflex describes unilateral lacrimation when a person eats or drinks[14]. The lines beginning with a dot indicate axons originating in the structure containing the dot. The oculomotor nerve is responsible for the efferent limb of the pupillary reflex; it drives the iris muscles that constrict the pupil.[1]. Supraoculomotor nucleus is incorrect because it is involved in the pupillary accommodation response and not in the pupillary light reflex response. Sphincter Pupillae- constrictor muscle that is innervated by the Parasympathetic nervous system innvervated by Oculomotor Nerve (CN3) Dilator Pupillae- dilator muscle that is innervated by the sympathetic nervous system Pathway of Pupillary Light Constriction Pathway: The ophthalmic division of the trigeminal nerve carries impulses to the main sensory nucleus of the trigeminal nerve. Were the solution steps not detailed enough? The Basilica-Cathedral of Our Lady of the Pillar (Spanish: Catedral-Baslica de Nuestra Seora del Pilar) is a Roman Catholic church in Zaragoza, Aragon, Spain.The Basilica worships Blessed Virgin Mary, under her title Our Lady of the Pillar.According to its website, this church is the first church dedicated to Mary. The distinction between the light-reflex and near-reflex pathways forms the basis for some forms of pupillary light-near dissociation (i.e., pupils that do not react to light but react to near stimuli) in which the dorsal midbrain and pretectal nuclei are damaged, but the near-reflex pathways and the Edinger-Westphal nuclei are spared ( Fig . However, light directed in the right eye will elicit pupillary responses in the right eye and the left (blind) eye. [12][13] This shows that the pupillary light reflex is modulated by subjective (as opposed to objective) brightness. By clicking Accept All, you consent to the use of ALL the cookies. Department of Neurobiology and Anatomy - Site webmaster: nba.webmaster@uth.tmc.edu, Instructional design and illustrations created through the Academic Technology. yesterday, Posted The OKN response can also be used to evaluate for suspected subclinical internuclear ophthalmoplegia, which will show a slower response by the medial rectus on the side of the lesion, and for suspected Parinauds syndrome, in which the use of a downward OKN target will accentuate convergent retraction movements on attempted upgaze. Montoya FJ, Riddell CE, Caesar R, Hague S. Treatment of gustatory hyperlacrimation (crocodile tears) with injection of botulinum Note that reflex responses are initiated by sensory stimuli that activate afferent neurons (e.g., somatosensory stimuli for the eye blink reflex and visual stimuli for the pupillary light reflex and accommodation responses). Contour: you should comment on the outline of the disc which should be smooth and well-defined. VOR can be evaluated using an ophthalmoscope to view the optic disc while the patient rotates his or her head; if the VOR is abnormal, catch-up saccades will manifest as jerkiness of the optic disc. T This building is one of the 12 Treasures of Spain. Pathway: Short ciliary nerves come together at the ciliary ganglion and converge with the long ciliary nerve to form the ophthalmic division of the trigeminal nerve, which continues to the Gasserian ganglion and then the main sensory nucleus of the trigeminal nerve[17][18]. Relations Dilator pupillae muscle of iris Musculus dilatator pupillae iridis 1/5 Synonyms: Radial muscle of iris, Musculus dilator pupillae iridis There are no other motor symptoms. In this chapter you will learn of the structures normally involved in performing these ocular responses and the disorders that result from damage to components of neural circuit controlling these responses. Ciliary muscle dysfunction gradually improves over several months as injured axons regenerate and reinnervate the ciliary muscle, and the pupil becomes smaller over time. :sphincter pupilae. D View Available Hint(s) Reset Help Optic nerve Retinal photoreceptors Sphincter pupillae Midbrain Ciliary ganglion Oculomotor nervo Stimulus Receptor Sensory Integration Efectos neuron Submit. Its motor neurons innervate the lateral rectus muscle. Furthermore, segment 4 shares the same anatomical space in the midbrain as segment 3, therefore segment 4 will likely be affected if segment 3 is damaged. Local ocular disease such as blowout fractures of the orbital floor, infiltrative orbital pseudotumors, and restrictive syndromes may show an absent Bells reflex. The muscle itself consists of six to eight circles of smooth muscle fibers, between of which are found the nerves and blood vessels that supply each fiber. Pupillary Reflex - an overview | ScienceDirect Topics The Optic Nerve. Pupillary reflex is conceptually linked to the side (left or right) of the reacting pupil, and not to the side from which light stimulation originates. (a) Rank the magnitudes of his acceleration at the points A,B,C,DA, B, C, DA,B,C,D, and EEE, from largest to smallest. Observation: You observe that the patient has normal vision but that his pupils, You conclude that his eye's functional loss is, Pathway(s) affected: You conclude that structure(s) in the, Side & Level of damage: As the pupillary response deficit. In supranuclear palsy, which can occur with Steele-Richardson syndrome, Parinauds syndrome, and double elevator palsy, patients cannot elevate their eyes but can do so on attempting the Bells phenomenon. Diplopia, ptosis, and impaired extraocular movements on the . The patient complains of pain in her left eye. The pupillary light reflex(PLR) or photopupillary reflexis a reflexthat controls the diameter of the pupil, in response to the intensity (luminance) of light that falls on the retinal ganglion cellsof the retinain the back of the eye, thereby assisting in adaptationof vision to various levels of lightness/darkness. The decreased tension allows the lens to increase its curvature and refractive (focusing) power. The optokinetic reflex, or optokinetic nystagmus, consists of two components that serve to stabilize images on the retina: a slow, pursuit phase and a fast reflex or refixation phase [15]. Human nervous system - Reflex actions | Britannica These cookies track visitors across websites and collect information to provide customized ads. The pupil is the space within the eye that permits light to project onto the retina. lens [3] Each afferent limb has two efferent limbs, one ipsilateral and one contralateral. Expl. 1996;36(9):568-573. The ciliary muscles, which control the position of the ciliary processes and the tension on the zonule, control the shape of the lens. The ciliospinal reflex is pupillary dilation in response to noxious stimuli, such as pinching, to the face, neck, or upper trunk. Intrinsic reflexes are inborn and serve to protect the body. The lines ending with an arrow indicate axons terminating in the structure at the tip of the arrow. The accommodation pathway includes the supraoculomotor area, which functions as a "higher-order" motor control stage controlling the motor neurons and parasympathetic neurons (i.e., the Edinger-Westphal neurons) of the oculomotor nucleus. ( Observe the reaction to a wisp of cotton touching the patient's left and right cornea. The neural pathway of the pupillary light reflex as first described by Wernicke [1, 2] in 1880s consists of four neurons (Fig. In this chapter we will start at the level of reflex responses and move onto more complex voluntary responses in the following lecture. (allowing less light in), whereas lower intensity light causes the pupil to become larger Mydriasis, Sensitivity and Specificity Biostatistics Video Lecture, Vertical Mattress Suture Video Instruction, Pharmacokinetics Excretion Video Tutorial Made Easy, What Are Acute Pancreatitis Symptoms, Causes, Diagnosis, Treatment, Anti-aging Gene Therapy Injections Could Rewind Heart Age by 10 Years, The teen brain tunes out moms voice in favor of more unfamiliar voices, U.S. obesity epidemic The Role of Age, Sex and Race, Genetic Screening Lets Parents Pick the Healthiest Embryos, Study Shows Children Sleeping 10 Hours A Night Demonstrate More Success in Emotional Development, Learning, Surprising Benefits of Virovores: An Organism That Eats Viruses, What are Scoliosis Symptoms, Causes, Diagnosis and Treatment Options, Study Shows Children Sleeping 10 Hours A Night Demonstrate More Success in. 4.) Isolated accommodation deficits can occur in healthy persons or in patients with neurological or systemic conditions (such as in children after a viral illness and in women before or after childbirth). Part B - Pupillary Light Reflex Pathway Drag The Labels To Identify The Five Basic Components Of The Pupillary Light Reflex Pathway. This cookie is set by GDPR Cookie Consent plugin. Left consensual reflex is normal, therefore segments 2, 4, and 7 are normal. Get it solved from our top experts within 48hrs! There are various other stimuli that can induce a trigeminal blink reflex by stimulating the ophthalmic division of the trigeminal nerve, including a gentle tap on the forehead, cutaneous stimulation, or supraorbital nerve stimulation[4]. Pupillary Light Reflex Pathway, is a reflex that controls the diameter of the pupil, in response to the intensity (luminance) of light that falls on the retina of the eye, thereby assisting in adaptation to various levels of darkness and light, in addition to retinal sensitivity. The pretectal nucleus projects crossed and uncrossed fibers to the ipsilateral and contralateral Edinger-Westphal nuclei, which are also located in the midbrain. Figure 7.10 The patient cannot detect pinpricks to his left forehead. There are no other motor symptoms. Solved Part B - Pupillary Light Reflex Pathway Drag the - Chegg {\displaystyle T_{p}} A direct pupillary reflex is pupillary response to light that enters the ipsilateral (same) eye. The right pupil appears normal in size and reacts to light when it is directed in the right or left eye. The efferent part of the pathway (blue) is the impulse/message that is sent from the mid-brain back to both pupils via the ciliary ganglion and the third cranial nerve (the oculomotor nerve), causing both pupils to constrict, even even though only one eye is being stimulated by the light. The reflex is classically tested with an optokinetic drum or tape with alternating stripes of varying spatial frequencies. Five Components of the Reflex Arc: 1. receptor 2. afferent pathway (sensory neurons) 3. integration center 4. efferent pathway (motor neurons) 5. effector Reflex Arc the pathway through which a stimulus can directly cause a response involuntarily Receptor (reflex arc component) detects the stimulus Afferent Pathway (reflex arc component) Privacy Policy, (Hide this section if you want to rate later). Figure 7.6 t Which of the following statements does not describe the procedure for testing the pupillary light reflex as shown in the video? The complexity of the circuitry (the chain or network of neurons) controlling a ocular motor response increases with the level of processing involved in initiating, monitoring, and guiding the response. However, the responses to light in both eyes may be weaker because of the reduced afferent input to the ipsilesional pretectal area. The presence or absence of Bells reflex can be useful in diagnosis of many systemic and local diseases[11]. I am currently continuing at SunAgri as an R&D engineer. The accommodation reflex (or accommodation-convergence reflex) is a reflex action of the eye, in response to focusing on a near object, then looking at a distant object (and vice versa), comprising coordinated changes in vergence, lens shape (accommodation) and pupil size. See more. -Measure the diameter of the left pupil in normal lighting. {\displaystyle \Phi (t-\tau )} It will be present in newborns, semi-obtunded patients, and patients who are attempting to malinger. Segment 2 is the afferent limb. Section of the parasympathetic preganglionic (oculomotor nerve) or postganglionic (short ciliary nerve) innervation to one eye will result in a loss (motor) of both the direct and consensual pupillary light responses of the denervated eye. 2017;9(12):e2004. Eyes directed nasally during accommodation. Ophthalmologic considerations: The corneal reflex can be utilized as a test of corneal sensation in patients who are obtunded or semicomatose[4]. This website uses cookies to improve your experience while you navigate through the website. Symptoms. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. {\displaystyle \mathrm {d} t_{c}} Bell palsy: Clinical examination and management. as well as parasympathetic preganglionic axons to the ciliary ganglion. Short ciliary nerves leave the ciliary ganglion to innervate the constrictor muscle of the iris. are the derivatives for the This extensive pathway is being tested when a light is shined in the eyes.

Jess Hilarious Parents, Articles F

five basic components of the pupillary light reflex pathway

five basic components of the pupillary light reflex pathway